General Information
SPKB ID SPKB06740
Signal sequence MKKNIVCSIFALLLAFAVSQPSYA
Length 24
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..24
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 11.01(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06740.cif
Physicochemical Information
Molecular weight 2615.18724
Aliphatic index 122.0833333
Isoelectric point 9.405774727
Charge (pH=7) 1.934569102
Topological polar surface area 942.97
Aromaticity 0.125
Average rotatable bonds 3.5
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 35
X logP energy -5.8306
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
