SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06738

Signal sequence   MAGLRVSLLIIAALMAVAAAG

Length  21

Organism  Bacillus licheniformis strain 3F-3

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Cell membrane

Secretion efficiency  Nattokinase yield: 16.35(FU/mL)

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06738.cif

Structure  SPKB06738.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2012.54314

Aliphatic index  172.3809524

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  727.45

Aromaticity  0

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -4.15323

Hydropathy 



Literature Information


Title  High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase

DOI  10.1111/jam.13175,

Publication Year  2016

PubMed ID  27159567,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.