SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06731

Signal sequence   MKKFALLFIALVTAVVISACGNQSTSSKG

Length  29

Organism  Bacillus subtilis WB600

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Cell membrane

Secretion efficiency  CotA-laccase yield: 23.7(U/ml)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06731.cif

Structure  SPKB06731.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2985.59344

Aliphatic index  111.0344828

Isoelectric point  10.51301932

Charge (pH=7)   2.935124482

Topological polar surface area  1163.74

Aromaticity  0.068965517

Average rotatable bonds  3.482758621

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  43

X logP energy  -12.0594

Hydropathy 



Literature Information


Title  Efficient secretory production of CotA-laccase and its application in the decolorization and detoxification of industrial textile wastewater

DOI  10.1007/s11356-015-4426-6,

Publication Year  2015

PubMed ID  25847445,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.