General Information
SPKB ID SPKB06716
Signal sequence MRGKKVWISLLFALALIFTMAFGSTSSAQA
Length 30
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..30
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Bacillus protease novo type yield: 0.83(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06716.cif
Physicochemical Information
Molecular weight 3246.91964
Aliphatic index 104.3333333
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 1201.42
Aromaticity 0.133333333
Average rotatable bonds 3.566666667
Number of hydrogen bond donors 44
Number of hydrogen bond acceptors 43
X logP energy -8.77173
Hydropathy
Literature Information
Title Optimization of Protease Secretion in Bacillus subtilis and Bacillus licheniformis by Screening of Homologous and Heterologous Signal Peptides
DOI 10.1128/AEM.01146-10,
Publication Year 2010
PubMed ID 20709850,
Patent ID NA,