General Information
SPKB ID SPKB06593
Signal sequence MPYLKRVLLLLVTGLFMSLFAVTATASA
Length 28
Organism Bacillus subtilis WB600
UniProt ID P04957,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Aminopeptidase yield: 4.82(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06593.cif
Physicochemical Information
Molecular weight 3027.76034
Aliphatic index 142.8571429
Isoelectric point 10.45492462
Charge (pH=7) 1.99683554
Topological polar surface area 1049.53
Aromaticity 0.107142857
Average rotatable bonds 3.428571429
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 39
X logP energy -4.54503
Hydropathy 
Literature Information
Title Construction of a highly active secretory expression system via an engineered dual promoter and a highly efficient signal peptide in Bacillus subtilis
DOI 10.1016/j.nbt.2016.01.005,
Publication Year 2016
PubMed ID 26820123,
Patent ID NA,
