General Information
SPKB ID SPKB06588
Signal sequence MKKKLAAGLTASAIVGTTLVVTPAEA
Length 26
Organism Bacillus subtilis WB600
UniProt ID O07532,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Aminopeptidase yield: 15.8(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06588.cif
Physicochemical Information
Molecular weight 2542.07294
Aliphatic index 116.5384615
Isoelectric point 10.506919
Charge (pH=7) 1.998874321
Topological polar surface area 998.54
Aromaticity 0
Average rotatable bonds 3.230769231
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 37
X logP energy -9.9205
Hydropathy 
Literature Information
Title Construction of a highly active secretory expression system via an engineered dual promoter and a highly efficient signal peptide in Bacillus subtilis
DOI 10.1016/j.nbt.2016.01.005,
Publication Year 2016
PubMed ID 26820123,
Patent ID NA,
