General Information
SPKB ID SPKB06582
Signal sequence MAKPLSKGGILVKKVLIAGAVGTAVLFGTLSSGIPGLPAADAQVAKA
Length 47
Organism Bacillus subtilis WB600
UniProt ID O31803,
Motif 1..47
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Aminopeptidase yield: 88.59(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06582.cif
Physicochemical Information
Molecular weight 4488.43924
Aliphatic index 124.6808511
Isoelectric point 10.97760256
Charge (pH=7) 3.996955614
Topological polar surface area 1687.19
Aromaticity 0.021276596
Average rotatable bonds 3.14893617
Number of hydrogen bond donors 57
Number of hydrogen bond acceptors 61
X logP energy -15.369
Hydropathy 
Literature Information
Title Construction of a highly active secretory expression system via an engineered dual promoter and a highly efficient signal peptide in Bacillus subtilis
DOI 10.1016/j.nbt.2016.01.005,
Publication Year 2016
PubMed ID 26820123,
Patent ID NA,
