SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06581

Signal sequence   MVYQTKRDVPVTLMIVFLILLIQADA

Length  26

Organism  Bacillus subtilis TEB1030

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06581.cif

Structure  SPKB06581.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2991.68394

Aliphatic index  157.3076923

Isoelectric point  6.441851479

Charge (pH=7)   -0.002271492

Topological polar surface area  1091.42

Aromaticity  0.076923077

Average rotatable bonds  3.769230769

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -3.65753

Hydropathy 



Literature Information


Title  Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria

DOI  10.1016/j.jmb.2006.07.034,

Publication Year  2006

PubMed ID  16930615,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.