General Information
SPKB ID SPKB06572
Signal sequence MKKLIMALVILGALGTSYISA
Length 21
Organism Bacillus subtilis TEB1030
UniProt ID O31926,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06572.cif
Physicochemical Information
Molecular weight 2193.77474
Aliphatic index 158.0952381
Isoelectric point 10.24760792
Charge (pH=7) 1.996543817
Topological polar surface area 778.28
Aromaticity 0.047619048
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 30
X logP energy -3.5266
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,