SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06563

Signal sequence   MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNA

Length  39

Organism  Bacillus subtilis TEB1030

UniProt ID  NA,

Motif  1..39



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06563.cif

Structure  SPKB06563.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4613.66954

Aliphatic index  92.56410256

Isoelectric point  12.98469593

Charge (pH=7)   11.93480296

Topological polar surface area  1962.73

Aromaticity  0.051282051

Average rotatable bonds  4.102564103

Number of hydrogen bond donors  76

Number of hydrogen bond acceptors  62

X logP energy  -18.42474

Hydropathy 



Literature Information


Title  Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria

DOI  10.1016/j.jmb.2006.07.034,

Publication Year  2006

PubMed ID  16930615,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.