General Information
SPKB ID SPKB06546
Signal sequence MKKKQVSHAIIISVMLSFVIAVFHTIHA
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06546.cif
Physicochemical Information
Molecular weight 3149.89284
Aliphatic index 135.7142857
Isoelectric point 11.10311933
Charge (pH=7) 3.269826471
Topological polar surface area 1137.13
Aromaticity 0.071428571
Average rotatable bonds 3.785714286
Number of hydrogen bond donors 40
Number of hydrogen bond acceptors 42
X logP energy -5.6526
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,