General Information
SPKB ID SPKB06529
Signal sequence MKLRKVLTGSVLSLGLLVSASPAFA
Length 25
Organism Bacillus subtilis TEB1030
UniProt ID O31925,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06529.cif
Physicochemical Information
Molecular weight 2559.14914
Aliphatic index 140.4
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 968.02
Aromaticity 0.04
Average rotatable bonds 3.4
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 35
X logP energy -8.02613
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
