General Information
SPKB ID SPKB06527
Signal sequence MRKKRVITCVMAASLTLGSLLPAGYATA
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID O31973,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06527.cif
Physicochemical Information
Molecular weight 2923.58684
Aliphatic index 108.2142857
Isoelectric point 10.88840969
Charge (pH=7) 3.934562479
Topological polar surface area 1137.45
Aromaticity 0.035714286
Average rotatable bonds 3.428571429
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 42
X logP energy -10.80526
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
