General Information
SPKB ID SPKB06504
Signal sequence MKKELLASLVLCLSLSPLVSTNEVFA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID O31635,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.08(U/ml)
Type Sec/SPI
Structure Information
PDB ID 9A4P,
Predicted Structure ID SPKB06504.cif
Physicochemical Information
Molecular weight 2806.41204
Aliphatic index 146.1538462
Isoelectric point 6.354537022
Charge (pH=7) -0.061030239
Topological polar surface area 1052.91
Aromaticity 0.038461538
Average rotatable bonds 3.615384615
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 39
X logP energy -7.5064
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
