General Information
SPKB ID SPKB06500
Signal sequence MDKFLNNRWAVKIIALLFALLLYVAVNS
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.11(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06500.cif
Physicochemical Information
Molecular weight 3236.95234
Aliphatic index 156.7857143
Isoelectric point 10.24365751
Charge (pH=7) 1.99698699
Topological polar surface area 1185.78
Aromaticity 0.142857143
Average rotatable bonds 3.785714286
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 39
X logP energy -3.57043
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,