General Information
SPKB ID SPKB06499
Signal sequence MKRRKFSSVVAAVLIFALIFSLFSPGTKAAA
Length 31
Organism Bacillus subtilis TEB1030
UniProt ID P54423,
Motif 1..31
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency Cutinase yield: 0.12(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06499.cif
Physicochemical Information
Molecular weight 3328.06564
Aliphatic index 110.3225806
Isoelectric point 12.54607567
Charge (pH=7) 4.997092575
Topological polar surface area 1230.54
Aromaticity 0.129032258
Average rotatable bonds 3.516129032
Number of hydrogen bond donors 45
Number of hydrogen bond acceptors 43
X logP energy -8.61476
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,