General Information
SPKB ID SPKB06498
Signal sequence MKKKLAAGLTASAIVGTTLVVTPAEA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID O07532,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.13(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06498.cif
Physicochemical Information
Molecular weight 2542.07294
Aliphatic index 116.5384615
Isoelectric point 10.506919
Charge (pH=7) 1.998874321
Topological polar surface area 998.54
Aromaticity 0
Average rotatable bonds 3.230769231
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 37
X logP energy -9.9205
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,