General Information
SPKB ID SPKB06496
Signal sequence MKRLLSTLLIGIMLLTFAPSAFA
Length 23
Organism Bacillus subtilis TEB1030
UniProt ID P38422,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.14(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06496.cif
Physicochemical Information
Molecular weight 2508.16204
Aliphatic index 148.6956522
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 863.57
Aromaticity 0.086956522
Average rotatable bonds 3.565217391
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 32
X logP energy -3.23993
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,