General Information
SPKB ID SPKB06493
Signal sequence MKKLLTVMTMAVLTAGTLLLPAQSVTPAAHA
Length 31
Organism Bacillus subtilis TEB1030
UniProt ID P25152,
Motif 1..31
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.16(U/ml)
Type Sec/SPI
Structure Information
PDB ID 6HC6,
Predicted Structure ID SPKB06493.cif
Physicochemical Information
Molecular weight 3179.92904
Aliphatic index 122.9032258
Isoelectric point 10.80542203
Charge (pH=7) 2.088303323
Topological polar surface area 1163.93
Aromaticity 0
Average rotatable bonds 3.290322581
Number of hydrogen bond donors 40
Number of hydrogen bond acceptors 45
X logP energy -9.405
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,