General Information
SPKB ID SPKB06488
Signal sequence MGMKKKLSLGVASAALGLALVGGGTWA
Length 27
Organism Bacillus subtilis TEB1030
UniProt ID P54507,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.29(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06488.cif
Physicochemical Information
Molecular weight 2588.16504
Aliphatic index 112.2222222
Isoelectric point 11.10307074
Charge (pH=7) 2.997099198
Topological polar surface area 974.46
Aromaticity 0.037037037
Average rotatable bonds 3.259259259
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 36
X logP energy -8.5839
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
