General Information
SPKB ID SPKB06487
Signal sequence MKKIWIGMLAAAVLLLMVPKVSLADA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.29(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06487.cif
Physicochemical Information
Molecular weight 2783.57154
Aliphatic index 157.6923077
Isoelectric point 10.50691891
Charge (pH=7) 1.997545682
Topological polar surface area 933.41
Aromaticity 0.038461538
Average rotatable bonds 3.576923077
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 35
X logP energy -1.1166
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,