General Information
SPKB ID SPKB06485
Signal sequence MLKKKWMVGLLAGCLAAGGFSYNAFA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID O35012,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.3(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06485.cif
Physicochemical Information
Molecular weight 2748.35774
Aliphatic index 90.38461538
Isoelectric point 10.13347695
Charge (pH=7) 2.934274068
Topological polar surface area 968.22
Aromaticity 0.153846154
Average rotatable bonds 3.461538462
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 36
X logP energy -5.1678
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
