General Information
SPKB ID SPKB06478
Signal sequence MKWMCSICCAAVLLAGGAAQA
Length 21
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.49(U/ml)
Type Sec/SPI
Structure Information
PDB ID 1W17,
Predicted Structure ID SPKB06478.cif
Physicochemical Information
Molecular weight 2098.60044
Aliphatic index 98.0952381
Isoelectric point 8.045790785
Charge (pH=7) 0.811765118
Topological polar surface area 750.45
Aromaticity 0.047619048
Average rotatable bonds 3.19047619
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 30
X logP energy -6.3228
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
