General Information
SPKB ID SPKB06477
Signal sequence MRFTKVVGFLSVLGLAAVFPLTAQA
Length 25
Organism Bacillus subtilis TEB1030
UniProt ID O31805,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.52(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06477.cif
Physicochemical Information
Molecular weight 2637.22204
Aliphatic index 124.8
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 944.63
Aromaticity 0.12
Average rotatable bonds 3.32
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 33
X logP energy -5.41663
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
