General Information
SPKB ID SPKB06476
Signal sequence MMIKQCVICLSLLVFGTTAAHA
Length 22
Organism Bacillus subtilis TEB1030
UniProt ID O32019,
Motif 1..22
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.57(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06476.cif
Physicochemical Information
Molecular weight 2350.93944
Aliphatic index 128.6363636
Isoelectric point 8.241247528
Charge (pH=7) 0.964648925
Topological polar surface area 832.9
Aromaticity 0.045454545
Average rotatable bonds 3.5
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 33
X logP energy -5.4646
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
