General Information
SPKB ID SPKB06467
Signal sequence MRKTIFAFLTGLMMFGTITAASA
Length 23
Organism Bacillus subtilis TEB1030
UniProt ID P40407,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.92(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06467.cif
Physicochemical Information
Molecular weight 2480.03964
Aliphatic index 85.2173913
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 892.59
Aromaticity 0.130434783
Average rotatable bonds 3.52173913
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 34
X logP energy -6.51413
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,