General Information
SPKB ID SPKB06466
Signal sequence MKSKGSIMACLILFSFTITTFINTETISAFS
Length 31
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..31
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 0.94(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06466.cif
Physicochemical Information
Molecular weight 3404.05494
Aliphatic index 94.51612903
Isoelectric point 8.540504393
Charge (pH=7) 0.937194639
Topological polar surface area 1271.05
Aromaticity 0.129032258
Average rotatable bonds 3.64516129
Number of hydrogen bond donors 47
Number of hydrogen bond acceptors 49
X logP energy -11.7933
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,