General Information
SPKB ID SPKB06461
Signal sequence MKKRFSLIMMTGLLFGLTSPAFA
Length 23
Organism Bacillus subtilis TEB1030
UniProt ID P70960,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.17(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06461.cif
Physicochemical Information
Molecular weight 2561.20024
Aliphatic index 93.47826087
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 889.59
Aromaticity 0.130434783
Average rotatable bonds 3.695652174
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 34
X logP energy -4.64193
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
