General Information
SPKB ID SPKB06460
Signal sequence MKQFAITLSVLCALILLVPTLLVIPFQHNKEAGA
Length 34
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..34
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.28(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06460.cif
Physicochemical Information
Molecular weight 3693.55054
Aliphatic index 152.0588235
Isoelectric point 8.548069757
Charge (pH=7) 1.028103729
Topological polar surface area 1314.02
Aromaticity 0.058823529
Average rotatable bonds 3.529411765
Number of hydrogen bond donors 44
Number of hydrogen bond acceptors 47
X logP energy -6.0337
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,