General Information
SPKB ID SPKB06458
Signal sequence MKRMIVRMTLPLLIVCLAFSSFSASARA
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID O31455,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.31(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06458.cif
Physicochemical Information
Molecular weight 3113.89304
Aliphatic index 118.5714286
Isoelectric point 12.22275045
Charge (pH=7) 3.935704616
Topological polar surface area 1153.1
Aromaticity 0.071428571
Average rotatable bonds 3.678571429
Number of hydrogen bond donors 44
Number of hydrogen bond acceptors 42
X logP energy -8.39439
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,