General Information
SPKB ID SPKB06454
Signal sequence MFKKLLLATSALTFSLSLVLPLDGHAKA
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.41(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06454.cif
Physicochemical Information
Molecular weight 2986.64944
Aliphatic index 136.0714286
Isoelectric point 10.50698149
Charge (pH=7) 2.088454773
Topological polar surface area 1085.42
Aromaticity 0.071428571
Average rotatable bonds 3.535714286
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 40
X logP energy -6.4656
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,