General Information
SPKB ID SPKB06446
Signal sequence MKKSQYFIVFICFFVLFSVHPIAAAAA
Length 27
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.61(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06446.cif
Physicochemical Information
Molecular weight 3049.72814
Aliphatic index 108.5185185
Isoelectric point 9.407025159
Charge (pH=7) 2.025478192
Topological polar surface area 995.63
Aromaticity 0.222222222
Average rotatable bonds 3.481481481
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 37
X logP energy -1.9202
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
