General Information
SPKB ID SPKB06442
Signal sequence MKKKKTWKRFLHFSSAALAAGLIFTSAAPAEA
Length 32
Organism Bacillus subtilis TEB1030
UniProt ID P94522,
Motif 1..32
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.82(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06442.cif
Physicochemical Information
Molecular weight 3479.14684
Aliphatic index 73.75
Isoelectric point 11.36666267
Charge (pH=7) 5.089190032
Topological polar surface area 1331.55
Aromaticity 0.125
Average rotatable bonds 3.59375
Number of hydrogen bond donors 48
Number of hydrogen bond acceptors 47
X logP energy -10.40913
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,