General Information
SPKB ID SPKB06440
Signal sequence MKKIVSILFMFGLVMGFSQFQPSTVFA
Length 27
Organism Bacillus subtilis TEB1030
UniProt ID O34310,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.87(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06440.cif
Physicochemical Information
Molecular weight 3054.76004
Aliphatic index 93.7037037
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 1030.27
Aromaticity 0.185185185
Average rotatable bonds 3.703703704
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 39
X logP energy -4.4361
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,