General Information
SPKB ID SPKB06434
Signal sequence MRKNRILALFVLSLGLLSFMVTPVSA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID P37965,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 1.96(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06434.cif
Physicochemical Information
Molecular weight 2877.58604
Aliphatic index 146.1538462
Isoelectric point 12.51647815
Charge (pH=7) 2.997682643
Topological polar surface area 1055.86
Aromaticity 0.076923077
Average rotatable bonds 3.653846154
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 37
X logP energy -6.13336
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,