General Information
SPKB ID SPKB06431
Signal sequence MNFKKTVVSALSISALALSVSGVASA
Length 26
Organism Bacillus subtilis TEB1030
UniProt ID O31643,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 2.1(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06431.cif
Physicochemical Information
Molecular weight 2552.02464
Aliphatic index 123.8461538
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 1027.56
Aromaticity 0.038461538
Average rotatable bonds 3.269230769
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 38
X logP energy -12.4786
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
