General Information
SPKB ID SPKB06427
Signal sequence MKKIVAAIVVIGLVFIAFFYLYSRSGDVYQSVDA
Length 34
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..34
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 2.3(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06427.cif
Physicochemical Information
Molecular weight 3784.51484
Aliphatic index 131.7647059
Isoelectric point 9.031802979
Charge (pH=7) 0.995732646
Topological polar surface area 1376.63
Aromaticity 0.176470588
Average rotatable bonds 3.588235294
Number of hydrogen bond donors 49
Number of hydrogen bond acceptors 48
X logP energy -6.00913
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,