General Information
SPKB ID SPKB06424
Signal sequence MVKKWLIQFAVMLSVLSTFTYSASA
Length 25
Organism Bacillus subtilis TEB1030
UniProt ID O31436,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 2.51(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06424.cif
Physicochemical Information
Molecular weight 2822.41654
Aliphatic index 109.2
Isoelectric point 10.24760792
Charge (pH=7) 1.996543817
Topological polar surface area 1014.25
Aromaticity 0.16
Average rotatable bonds 3.64
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 38
X logP energy -5.8362
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,