General Information
SPKB ID SPKB06423
Signal sequence MKKLVLCVSILAVILSGVA
Length 19
Organism Bacillus subtilis TEB1030
UniProt ID NA,
Motif 1..19
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 2.53(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06423.cif
Physicochemical Information
Molecular weight 1957.54754
Aliphatic index 194.7368421
Isoelectric point 9.676237541
Charge (pH=7) 1.935419516
Topological polar surface area 679.62
Aromaticity 0
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -2.378
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,