General Information
SPKB ID SPKB06414
Signal sequence MKKRLIAPMLLSAASLAFFAMSGSAQA
Length 27
Organism Bacillus subtilis TEB1030
UniProt ID P39848,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 3.33(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06414.cif
Physicochemical Information
Molecular weight 2812.44264
Aliphatic index 98.14814815
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 1049.08
Aromaticity 0.074074074
Average rotatable bonds 3.481481481
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 39
X logP energy -8.98883
Hydropathy 
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,
