General Information
SPKB ID SPKB06412
Signal sequence MKKKQVMLALTAAAGLGLTALHSAPAAKA
Length 29
Organism Bacillus subtilis TEB1030
UniProt ID O31579,
Motif 1..29
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 3.67(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06412.cif
Physicochemical Information
Molecular weight 2863.51634
Aliphatic index 108.2758621
Isoelectric point 11.27834369
Charge (pH=7) 4.087713255
Topological polar surface area 1105.87
Aromaticity 0
Average rotatable bonds 3.344827586
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 41
X logP energy -10.1853
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,