General Information
SPKB ID SPKB06411
Signal sequence MKRLFMKASLVLFAVVFVFAVKGAPAKA
Length 28
Organism Bacillus subtilis TEB1030
UniProt ID O34554,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Cutinase yield: 3.8(U/ml)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06411.cif
Physicochemical Information
Molecular weight 3040.85154
Aliphatic index 115
Isoelectric point 11.99738138
Charge (pH=7) 4.996800853
Topological polar surface area 1026.44
Aromaticity 0.142857143
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 37
X logP energy -2.58823
Hydropathy
Literature Information
Title Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria
DOI 10.1016/j.jmb.2006.07.034,
Publication Year 2006
PubMed ID 16930615,
Patent ID NA,