SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06408

Signal sequence   TYDAFLRAYQSWNTFVNPDRPNL

Length  23

Organism  Schizosaccharomyces pombe

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06408.cif

Structure  SPKB06408.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2789.05874

Aliphatic index  55.2173913

Isoelectric point  6.43653666

Charge (pH=7)   -0.002830183

Topological polar surface area  1173.64

Aromaticity  0.217391304

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  37

X logP energy  -10.90816

Hydropathy 



Literature Information


Title  LC-MS/MS quantification of bacterial and fungal signal peptides via direct injection: a case study of cross-kingdom communication

DOI  10.1007/s00216-025-05767-6,

Publication Year  2025

PubMed ID  39903273,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.