SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06406

Signal sequence   WHWLQLKPQPMY

Length  12

Organism  Saccharomyces cerevisiae

UniProt ID  NA,

Motif  1..12



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06406.cif

Structure  SPKB06406.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1626.93904

Aliphatic index  65

Isoelectric point  9.300695891

Charge (pH=7)   1.087747942

Topological polar surface area  558.53

Aromaticity  0.25

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  19

X logP energy  0.6109

Hydropathy 



Literature Information


Title  LC-MS/MS quantification of bacterial and fungal signal peptides via direct injection: a case study of cross-kingdom communication

DOI  10.1007/s00216-025-05767-6,

Publication Year  2025

PubMed ID  39903273,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.