SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06402

Signal sequence   MQPSSLLPLALCLLAAPA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06402.cif

Structure  SPKB06402.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1809.25544

Aliphatic index  152.2222222

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  615.2

Aromaticity  0

Average rotatable bonds  2.944444444

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  24

X logP energy  -3.5523

Hydropathy 



Literature Information


Title  Signal Peptides and Their Fragments in Post-Translation: Novel Insights of Signal Peptides

DOI  10.3390/ijms252413534,

Publication Year  2024

PubMed ID  39769297,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.