SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06399

Signal sequence   MKYLLPTAAAGLLLLAAQPAMA

Length  22

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  1QOK,

Predicted Structure ID  SPKB06399.cif

Structure  SPKB06399.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2228.77964

Aliphatic index  138.1818182

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  766.41

Aromaticity  0.045454545

Average rotatable bonds  3.136363636

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -3.1314

Hydropathy 



Literature Information


Title  N-Terminal Sequences of Signal Peptides Assuming Critical Roles in Expression of Heterologous Proteins in Bacillus subtilis

DOI  10.3390/microorganisms12071275,

Publication Year  2024

PubMed ID  39065044,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.