SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06398

Signal sequence   MKKRKRRNFKRFIAAFLVLALMISLVPA

Length  28

Organism  Bacillus subtilis

UniProt ID  Q07833,

Motif  1..28



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06398.cif

Structure  SPKB06398.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3319.21214

Aliphatic index  118.5714286

Isoelectric point  12.99206258

Charge (pH=7)   7.996790919

Topological polar surface area  1255.23

Aromaticity  0.107142857

Average rotatable bonds  4.107142857

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  41

X logP energy  -5.66662

Hydropathy 



Literature Information


Title  N-Terminal Sequences of Signal Peptides Assuming Critical Roles in Expression of Heterologous Proteins in Bacillus subtilis

DOI  10.3390/microorganisms12071275,

Publication Year  2024

PubMed ID  39065044,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.