SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06397

Signal sequence   MKFVKRRIIALVTILMLSVTSLFALQPSA

Length  29

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06397.cif

Structure  SPKB06397.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3248.07844

Aliphatic index  147.9310345

Isoelectric point  12.53174703

Charge (pH=7)   3.997387609

Topological polar surface area  1189.41

Aromaticity  0.068965517

Average rotatable bonds  3.75862069

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -6.34446

Hydropathy 



Literature Information


Title  N-Terminal Sequences of Signal Peptides Assuming Critical Roles in Expression of Heterologous Proteins in Bacillus subtilis

DOI  10.3390/microorganisms12071275,

Publication Year  2024

PubMed ID  39065044,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.