SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06396

Signal sequence   MARSIVKKSILLWIVISVLVLAFALTLIFTMAFSNMSVQA

Length  40

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..40



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06396.cif

Structure  SPKB06396.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4427.51784

Aliphatic index  156

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1555.74

Aromaticity  0.1

Average rotatable bonds  3.675

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  56

X logP energy  -6.71123

Hydropathy 



Literature Information


Title  Increased Expression Levels of Thermophilic Serine Protease TTHA0724 through Signal Peptide Screening in Bacillus subtilis and Applications of the Enzyme

DOI  10.3390/ijms242115950,

Publication Year  2023

PubMed ID  37958933,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.