SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06393

Signal sequence   MTKKAWFLPLVCVLLISGWLAPAASASA

Length  28

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06393.cif

Structure  SPKB06393.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2945.61724

Aliphatic index  125.7142857

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  995.98

Aromaticity  0.107142857

Average rotatable bonds  3.178571429

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -4.171

Hydropathy 



Literature Information


Title  Increased Expression Levels of Thermophilic Serine Protease TTHA0724 through Signal Peptide Screening in Bacillus subtilis and Applications of the Enzyme

DOI  10.3390/ijms242115950,

Publication Year  2023

PubMed ID  37958933,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.